Well, the N10 is more than twice as big (100x100 vs 85x54) and one USB 3 port sticking out one side and the other one at the opposing end makes the total installation even bulkier. For that larger footprint there are a lot of good boards available, some of which perform considerably better than the RK3399 for not that much more.
There is so many hardware on the market that looks cool, its great on paper, but you actually can’t use it for real, is driven by closed source, is supported only by vendor, etc. Everything matters.
Yes, its indeed case dependent. I strongly agree on that, but Antutu score is usually not exactly a use case.
Orangepi 4B is RK3399 with NPU on board.
And Debian and Ubuntu has nothing in common with hardware functions.