Yeah I would not swap the mounts to the 2007 PicoITX format as the mounts just steal I/O space and think that is one of the best features.
It would be great if they did a 1U panel as someone will do the math of how many you could fit side by side in 1U or more.
Thats why I like all the I/O on one plane as maybe I/O punch outs could be a thing but even Raspberry can not seem to keep to a singular compatible format.
Also the NVME mounts on board without some horrid riser in a bad attempt as a pseudo Pi format, is a huge plus.
Generally I like the format think its actually a big improvement on the Pi but doubt we will ever get a really universal format.
96boards was the same and also a sort of similar fail really.
Format wise apart from the cuteness of Zero type boards the Rock5B I would say is a definite fave.
That might be a Rock5A though as eagerly await whatever that maybe.
Maybe they might just do a single I/O punched out panel that is just a flat piece of thin steel with a big enough bezel (overlap) with mounting holes, that you can make a cut out and cover on any case, big enough?
More of a tidy than structural that just covers what makers may dremmel out?