No, it’s not too big. The size of the RK3588 is 23x23mm (I checked on the Rockchip website), if you are planning on getting the passive heatsink, get one that is 25x25mm. But in my trials of the passive heatsink, RK3588 was getting to about 45-50C. I switched to this one, https://www.amazon.com/dp/B00O4UIZ86?ref=ppx_yo2ov_dt_b_product_details&th=1, and it is consistently running at 25-28C.
146mm x 102 mm is the size of the whole mini-ITX board, not the chip.